Interactor 1: HCH1 (P53834)
Hsp90 co-chaperone HCH1 (High-copy Hsp90 suppressor protein 1)
Gene: HCH1

Interactor 2: AHA1 (Q12449)
Hsp90 co-chaperone AHA1 (Activator of Hsp90 ATPase protein 1)
Gene: AHA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.814

The method score is based on:

Property Details
Experiments 14739935, 12604615, unassigned1933
Identification Methods x-ray crystallography, two hybrid, dihydrofolate reductase reconstruction
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Aha1_N~Aha1_N
Common GO terms GO:0001671 - ATPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006457 - protein folding
GO:0051087 - protein-folding chaperone binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 153
Sc

1 350
+ Sc

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Last updated: 15 Jul 2024