HitPredict

Interactor 1: IST1 (P53843)
Vacuolar protein sorting-associated protein IST1 (Increased sodium tolerance protein 1)
Gene: IST1

Interactor 2: VPS60 (Q03390)
Vacuolar protein-sorting-associated protein 60 (Charged multivesicular body protein 5)
Gene: VPS60

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31273031, 35445263
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0015031 - protein transport GO:0032511 - late endosome to vacuole transport via multivesicular body sorting pathway
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 298 Sc			1 229
+	Sc
		764867 IST1_YEAST (1-298): 9.42e-92: 275: 100.00		SNF7_YEAST (4-226): 1.29e-34: 125: 20.98
+	Sc
		865243 IST1_YEAST (1-298): 9.42e-92: 275: 100.00		VPS20_YEAST (6-227): 1.29e-33: 122: 17.12
+	Hs
		867071 IST1_HUMAN (11-204): 5.78e-62: 201: 32.14		CHMP5_HUMAN (1-225): 7.1e-43: 146: 28.44
+	Ce
		106468 G5EDV6_CAEEL (9-195): 8.33e-60: 198: 31.25		Q18886_CAEEL (2-222): 2.41e-42: 144: 19.46
+	Dm
		116117 M9PHL4_DROME (7-197): 4.03e-59: 195: 29.74		CHMP5_DROME (1-228): 9.42e-43: 145: 27.19
+	Ce
		106465 G5EDV6_CAEEL (9-195): 8.33e-60: 198: 31.25		O16458_CAEEL (1-218): 1.81e-40: 139: 27.06
+	Hs
		867066 IST1_HUMAN (11-204): 5.78e-62: 201: 32.14		CHM4B_HUMAN (15-220): 3.6e-38: 133: 19.42
+	Dm
		116103 M9PHL4_DROME (7-197): 4.03e-59: 195: 29.74		CHM4_DROME (2-222): 5.59e-38: 133: 17.78
+	Ce
		106469 G5EDV6_CAEEL (9-195): 8.33e-60: 198: 31.25		Q9BL60_CAEEL (7-219): 1.61e-28: 108: 13.15