HitPredict

Interactor 1: VPS75 (P53853)
Vacuolar protein sorting-associated protein 75
Gene: VPS75

Interactor 2: H3 (P61830)
Histone H3
Gene: HHT1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	17344218, 19172749
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 264 Sc			1 136
+	Hs
		1086346 TSYL4_HUMAN (16-235): 3.23e-69: 220: 15.32		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Hs
		934935 TSYL5_HUMAN (16-231): 2.59e-58: 192: 19.09		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		934666 SET_HUMAN (6-216): 4.04e-59: 191: 18.27		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		952444 TSYL5_HUMAN (16-231): 2.59e-58: 192: 19.09		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		952277 SET_HUMAN (6-216): 4.04e-59: 191: 18.27		H33_HUMAN (1-136): 1.25e-61: 187: 90.44
+	Hs
		963827 SET_HUMAN (6-216): 4.04e-59: 191: 18.27		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Hs
		963844 SET_HUMAN (6-216): 4.04e-59: 191: 18.27		H32_HUMAN (1-136): 6.6e-61: 185: 88.97
+	At
		886475 NAP1B_ARATH (5-221): 6.95e-57: 188: 15.04		H33_ARATH (1-136): 4.81e-62: 187: 87.50
+	Sc
		730877 VPS75_YEAST (1-264): 1.43e-77: 237: 100.00		CENPA_YEAST (24-134): 7.32e-41: 137: 53.04
+	At
		886672 NAP1B_ARATH (5-221): 6.95e-57: 188: 15.04		H31_ARATH (1-136): 1.66e-60: 184: 87.50
+	At
		886474 NAP1A_ARATH (5-222): 1.1e-54: 182: 13.06		H33_ARATH (1-136): 4.81e-62: 187: 87.50
+	Hs
		876755 NP1L1_HUMAN (1-217): 6.27e-54: 180: 13.78		H31_HUMAN (1-136): 3.24e-62: 188: 88.97
+	Hs
		1086291 NP1L4_HUMAN (5-225): 1.39e-54: 181: 13.95		H31T_HUMAN (1-136): 1.96e-61: 186: 86.03
+	Hs
		1174639 NP1L4_HUMAN (5-225): 1.39e-54: 181: 13.95		H32_HUMAN (1-136): 6.6e-61: 185: 88.97
+	At
		886466 NAP1C_ARATH (5-223): 7.42e-54: 179: 12.69		H33_ARATH (1-136): 4.81e-62: 187: 87.50
+	At
		886671 NAP1A_ARATH (5-222): 1.1e-54: 182: 13.06		H31_ARATH (1-136): 1.66e-60: 184: 87.50
+	Hs
		876827 NP1L1_HUMAN (1-217): 6.27e-54: 180: 13.78		H32_HUMAN (1-136): 6.6e-61: 185: 88.97
+	At
		886665 NAP1C_ARATH (5-223): 7.42e-54: 179: 12.69		H31_ARATH (1-136): 1.66e-60: 184: 87.50
+	Dm
		356123 Q9W1G7_DROME (20-263): 1.69e-49: 168: 14.98		H3_DROME (1-136): 6.6e-61: 185: 88.97
+	Sp
		1336870 YO48_SCHPO (10-219): 1.42e-39: 139: 27.65		CENPA_SCHPO (38-133): 9.18e-42: 136: 59.80