HitPredict

Interactor 1: CSL4 (P53859)
Exosome complex component CSL4 (CEP1 synthetic lethal protein 4)
Gene: CSL4

Interactor 2: RRP40 (Q08285)
Exosome complex component RRP40 (Ribosomal RNA-processing protein 40)
Gene: RRP40

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 0.60 0.741

The method score is based on:

Property Details
Experiments 16829593, 25210768, 33326748, 18314965, 37968396, 16729021, 21072061
Identification Methods affinity chromatography technology, tandem affinity purification, molecular sieving, electron microscopy
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
and 6 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 292
Sc

1 240
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024