HitPredict

Interactor 1: NOP15 (P53927)
Ribosome biogenesis protein 15 (Nucleolar protein 15)
Gene: NOP15

Interactor 2: HAS1 (Q03532)
ATP-dependent RNA helicase HAS1 (EC 3.6.4.13) (Helicase associated with SET1 protein 1)
Gene: HAS1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.751

Property	Details
Experiments	11805826, 16429126, 17922018, 37968396, 25877921, 30568249, 31511893, 23788678, unassigned1262
Identification Methods	tandem affinity purification, affinity chromatography technology, two hybrid, two hybrid array, validated two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor GO:0042273 - ribosomal large subunit biogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 220 Sc			1 505
+	Hs
		1245873 MK67I_HUMAN (60-220): 8.1e-40: 139: 28.73		DDX55_HUMAN (43-486): 6.51e-172: 499: 37.45
+	Hs
		1027929 MK67I_HUMAN (60-220): 8.1e-40: 139: 28.73		DDX10_HUMAN (5-505): 1.4e-148: 448: 37.87
+	Hs
		1316910 MK67I_HUMAN (60-220): 8.1e-40: 139: 28.73		DDX18_HUMAN (2-492): 3.3e-139: 418: 59.76
+	Dm
		1363283 Q9VCY1_DROME (72-204): 1.41e-38: 138: 29.20		DDX18_DROME (8-500): 6.83e-136: 409: 58.59
+	Hs
		571585 MK67I_HUMAN (60-220): 8.1e-40: 139: 28.73		DDX5_HUMAN (4-449): 2.8e-131: 395: 30.22
+	Hs
		198838 RFOX2_HUMAN (19-183): 1.37e-35: 131: 19.88		DDX5_HUMAN (4-449): 2.8e-131: 395: 30.22
+	Hs
		1073611 SF3B4_HUMAN (79-209): 1.67e-27: 109: 19.85		DDX17_HUMAN (4-478): 1.71e-134: 407: 29.31
+	Hs
		1077436 ELAV1_HUMAN (85-207): 6.15e-25: 101: 18.70		DDX17_HUMAN (4-478): 1.71e-134: 407: 29.31
+	Mm
		857323 TIA1_MOUSE (86-216): 1.37e-21: 93.1: 18.80		DDX17_MOUSE (4-478): 4.53e-135: 406: 29.11
+	Hs
		571469 ELAV1_HUMAN (85-207): 6.15e-25: 101: 18.70		DDX5_HUMAN (4-449): 2.8e-131: 395: 30.22
+	Hs
		133858 PABP1_HUMAN (82-207): 1.24e-25: 105: 15.87		DDX3X_HUMAN (4-428): 1.25e-126: 385: 27.77
+	Hs
		134018 PABP4_HUMAN (89-207): 3.83e-25: 104: 17.65		DDX3X_HUMAN (4-428): 1.25e-126: 385: 27.77
+	Mm
		857351 TIA1_MOUSE (86-216): 1.37e-21: 93.1: 18.80		Q8BTS0_MOUSE (4-449): 2.92e-131: 395: 30.22
+	Mm
		936480 TIAR_MOUSE (85-207): 1.08e-20: 90.8: 15.94		DDX5_MOUSE (4-449): 2.93e-131: 395: 30.22
+	Hs
		134244 PUF60_HUMAN (11-173): 8.5e-21: 91.8: 20.83		DDX3X_HUMAN (4-428): 1.25e-126: 385: 27.77
+	Hs
		1316885 MK67I_HUMAN (60-220): 8.1e-40: 139: 28.73		DDX31_HUMAN (9-505): 3.72e-82: 274: 32.37
+	Sc
		699710 NOP15_YEAST (1-220): 1.29e-46: 155: 100.00		DRS1_YEAST (26-394): 3.8e-72: 245: 38.32
+	Hs
		1292650 MK67I_HUMAN (60-220): 8.1e-40: 139: 28.73		DDX27_HUMAN (44-441): 4.37e-71: 243: 37.04
+	Sc
		638830 NOP15_YEAST (1-220): 1.29e-46: 155: 100.00		SPB4_YEAST (56-488): 1.9e-61: 213: 33.41
+	Hs
		1316955 MK67I_HUMAN (60-220): 8.1e-40: 139: 28.73		DDX49_HUMAN (44-429): 8.79e-60: 206: 34.52