HitPredict

Interactor 1: NOP15 (P53927)
Ribosome biogenesis protein 15 (Nucleolar protein 15)
Gene: NOP15

Interactor 2: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	11805826, 16429126, 17922018, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0030687 - preribosome, large subunit precursor
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 220 Sc			1 291
+	Hs
		1255204 MK67I_HUMAN (60-220): 8.1e-40: 139: 28.73		BRX1_HUMAN (26-286): 1.92e-85: 261: 47.91
+	Hs
		1316881 MK67I_HUMAN (60-220): 8.1e-40: 139: 28.73		RPF2_HUMAN (1-285): 3.52e-77: 238: 17.57
+	Sc
		733890 NOP15_YEAST (1-220): 1.29e-46: 155: 100.00		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		866245 NOP15_YEAST (1-220): 1.29e-46: 155: 100.00		IMP4_YEAST (5-261): 1.73e-61: 198: 17.76
+	Hs
		1316887 MK67I_HUMAN (60-220): 8.1e-40: 139: 28.73		RPF1_HUMAN (7-251): 6.1e-62: 201: 17.13
+	Sc
		755312 NOP15_YEAST (1-220): 1.29e-46: 155: 100.00		RPF1_YEAST (4-252): 5.84e-52: 173: 14.40
+	Hs
		1316896 MK67I_HUMAN (60-220): 8.1e-40: 139: 28.73		SSF1_HUMAN (12-281): 5.67e-45: 160: 12.87
+	Sc
		754891 NOP15_YEAST (1-220): 1.29e-46: 155: 100.00		SSF1_YEAST (10-197): 9.05e-34: 129: 15.64
+	Sc
		866287 NOP15_YEAST (1-220): 1.29e-46: 155: 100.00		SSF2_YEAST (10-197): 8.32e-33: 127: 15.17