HitPredict

Interactor 1: ASI3 (P53983)
Probable ERAD-associated E3 ubiquitin-protein ligase ASI1 (EC 2.3.2.27) (Amino acid sensor-independent protein 3)
Gene: ASI3

Interactor 2: UBC7 (Q02159)
Ubiquitin-conjugating enzyme E2 7 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 7) (Ubiquitin carrier protein) (Ubiquitin-conjugating enzyme E2-18 kDa) (Ubiquitin-protein ligase)
Gene: UBC7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	25519137, 14690591
Identification Methods	protein complementation assay, pull down, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 676 Sc			1 165
+	Sc
		867312 ASI1_YEAST (86-676): 0: 715: 27.29		UBC7_YEAST (1-165): 1.28e-71: 214: 100.00