HitPredict

Interactor 1: MOT1 (P53985)
Monocarboxylate transporter 1 (MCT 1) (Solute carrier family 16 member 1)
Gene: SLC16A1

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31980649, 31871319, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030054 - cell junction GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 500 Hs			1 193
+	Hs
		866927 MOT1_HUMAN (1-500): 9.63e-90: 285: 100.00		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436222 MOT1_HUMAN (1-500): 9.63e-90: 285: 100.00		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		866917 MOT1_HUMAN (1-500): 9.63e-90: 285: 100.00		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545283 MOT1_HUMAN (1-500): 9.63e-90: 285: 100.00		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		866926 MOT1_HUMAN (1-500): 9.63e-90: 285: 100.00		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120361 MOT1_HUMAN (1-500): 9.63e-90: 285: 100.00		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		238225 MOT2_HUMAN (1-484): 7.28e-74: 243: 57.65		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		238227 MOT2_HUMAN (1-484): 7.28e-74: 243: 57.65		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		238218 MOT2_HUMAN (1-484): 7.28e-74: 243: 57.65		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		238228 MOT2_HUMAN (1-484): 7.28e-74: 243: 57.65		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		238224 MOT2_HUMAN (1-484): 7.28e-74: 243: 57.65		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		238220 MOT2_HUMAN (1-484): 7.28e-74: 243: 57.65		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		238223 MOT2_HUMAN (1-484): 7.28e-74: 243: 57.65		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		238226 MOT2_HUMAN (1-484): 7.28e-74: 243: 57.65		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120233 MOT2_HUMAN (1-484): 7.28e-74: 243: 57.65		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		179092 MOT4_HUMAN (6-498): 1.43e-63: 215: 40.49		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		179091 MOT4_HUMAN (6-498): 1.43e-63: 215: 40.49		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		179080 MOT4_HUMAN (6-498): 1.43e-63: 215: 40.49		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		179090 MOT4_HUMAN (6-498): 1.43e-63: 215: 40.49		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		120216 MOT4_HUMAN (6-498): 1.43e-63: 215: 40.49		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98