Interactor 1: IST1 (P53990)
IST1 homolog (hIST1) (Charged multivesicular body protein 8) (CHMP8) (Putative MAPK-activating protein PM28)
Gene: IST1

Interactor 2: CHM1B (Q7LBR1)
Charged multivesicular body protein 1b (CHMP1.5) (Chromatin-modifying protein 1b) (CHMP1b) (Vacuolar protein sorting-associated protein 46-2) (Vps46-2) (hVps46-2)
Gene: CHMP1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 0.60 0.690

The method score is based on:

Property Details
Experiments 33961781, 19477918, 26634441, 19525971
Identification Methods affinity chromatography technology, 3D electron microscopy, surface plasmon resonance, transmission electron microscopy, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0015031 - protein transport
GO:0019904 - protein domain specific binding
GO:0030496 - midbody
GO:0036258 - multivesicular body assembly
and 5 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 364
Hs

1 199
+ Hs
+ Hs
+ Dm
+ Dm
+ Ce
+ Dm
+ Dm
+ Dm
+ Dm
+ Ce
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024