HitPredict

Interactor 1: SC24C (P53992)
Protein transport protein Sec24C (SEC24-related protein C)
Gene: SEC24C

Interactor 2: SC23B (Q15437)
Protein transport protein Sec23B (hSec23B) (SEC23-related protein B)
Gene: SEC23B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.928

The method score is based on:

Property Details
Experiments 16189514, 35271311, 30596474, 33961781, 31515488
Identification Methods two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Gelsolin~Gelsolin, Gelsolin~Sec23_helical, Gelsolin~Sec23_trunk, Sec23_BS~Sec23_helical, Sec23_BS~Sec23_trunk, Sec23_BS~zf-Sec23_Sec24, Sec23_helical~Sec23_trunk, Sec23_trunk~Sec23_trunk, zf-Sec23_Sec24~zf-Sec23_Sec24
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0008270 - zinc ion binding
GO:0030127 - COPII vesicle coat
and 2 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1094
Hs

1 767
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce
+ Sp
+ Sc
+ Sc
+ Sp
+ Sp
+ Hs
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024