Interactor 1: TCP4 (P53999)
Activated RNA polymerase II transcriptional coactivator p15 (Positive cofactor 4) (PC4) (SUB1 homolog) (p14)
Gene: SUB1

Interactor 2: TCP4 (P53999)
Activated RNA polymerase II transcriptional coactivator p15 (Positive cofactor 4) (PC4) (SUB1 homolog) (p14)
Gene: SUB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.922

The method score is based on:

Property Details
Experiments 25416956, 32296183, 9360603, 16415882, unassigned1304
Identification Methods two hybrid, x-ray crystallography, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PC4~PC4
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001111 - RNA polymerase II promoter clearance
GO:0003697 - single-stranded DNA binding
GO:0003713 - transcription coactivator activity
GO:0003723 - RNA binding
and 9 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 127
Hs

1 127
+ At
+ At
+ At
+ Zm
+ Zm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024