Interactor 1: DPOG1 (P54098)
DNA polymerase subunit gamma-1 (EC 2.7.7.7) (3'-5' exodeoxyribonuclease) (EC 3.1.11.-) (5'-deoxyribose-phosphate lyase) (EC 4.2.99.-) (Mitochondrial DNA polymerase catalytic subunit) (PolG-alpha)
Gene: POLG
Interactor 2: DPOG2 (Q9UHN1)
DNA polymerase subunit gamma-2 (DNA polymerase gamma accessory 55 kDa subunit) (p55) (Mitochondrial DNA polymerase accessory subunit) (MtPolB) (PolG-beta)
Gene: POLG2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 0.90 | 0.909 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26496610, 28514442, 33961781, 19837034, 17762861, 16263719 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation, x-ray crystallography, electron microscopy, isothermal titration calorimetry, molecular sieving, pull down, surface plasmon resonance |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DNApol_Exo~HGTP_anticodon |
| Common GO terms | GO:0003887 - DNA-directed DNA polymerase activity GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix GO:0005760 - gamma DNA polymerase complex GO:0006261 - DNA-templated DNA replication and 2 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
