HitPredict

Interactor 1: ICLN (P54105)
Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI) (Reticulocyte pICln)
Gene: CLNS1A

Interactor 2: RUXE (P62304)
Small nuclear ribonucleoprotein E (snRNP-E) (Sm protein E) (Sm-E) (SmE)
Gene: SNRPE

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.939

The method score is based on:

Property Details
Experiments 28514442, 33961781, 11713266, 35271311, 18984161
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains LSM~Voldacs
Common GO terms GO:0000387 - spliceosomal snRNP assembly
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex
and 3 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 237
Hs

1 92
+ Ce
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024