HitPredict

Interactor 1: ICLN (P54105)
Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory protein ICln) (I(Cln)) (Chloride ion current inducer protein) (ClCI) (Reticulocyte pICln)
Gene: CLNS1A

Interactor 2: E41L3 (Q9Y2J2)
Band 4.1-like protein 3 (4.1B) (Differentially expressed in adenocarcinoma of the lung protein 1) (DAL-1) (Erythrocyte membrane protein band 4.1-like 3) [Cleaved into: Band 4.1-like protein 3, N-terminally processed]
Gene: EPB41L3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	24366813, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 237 Hs			1 1087
+	Hs
		640225 ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00		PTN3_HUMAN (90-701): 3.39e-122: 399: 23.67
+	Hs
		299251 ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00		FARP2_HUMAN (79-584): 1.98e-118: 392: 30.04
+	Hs
		867438 ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00		FRMD7_HUMAN (110-749): 7.76e-119: 384: 25.49
+	Hs
		204636 ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00		E41L2_HUMAN (583-1087): 1.39e-44: 177: 32.64
+	Hs
		505591 ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00		EPB41_HUMAN (701-1083): 3.49e-41: 166: 33.33
+	Hs
		867467 ICLN_HUMAN (1-237): 2.09e-113: 326: 100.00		E41L1_HUMAN (631-1084): 9.44e-23: 107: 21.33