Interactor 1: BLM (P54132)
RecQ-like DNA helicase BLM (EC 5.6.2.4) (Bloom syndrome protein) (DNA 3'-5' helicase BLM) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)
Gene: BLM

Interactor 2: TOP3A (Q13472)
DNA topoisomerase 3-alpha (EC 5.6.2.1) (DNA topoisomerase III alpha)
Gene: TOP3A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.983

The method score is based on:

Property Details
Experiments 11470874, 11406610, 12724401, 26496610, 10734115, 10825162, 30279242, 23509288, 35271311, 24239288, 20360068, 15775963, 20711169
Identification Methods far western blotting, affinity chromatography technology, pull down, tandem affinity purification, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~Toprim
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0003677 - DNA binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 6 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1417
Hs

1 1001
+ Xl
+ Hs
+ Hs
+ Hs
+ Hs
+ Sp
+ Dm
+ Sc
+ Ce
+ Ec
+ Ec

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Last updated: 15 Jul 2024