HitPredict

Interactor 1: BLM (P54132)
RecQ-like DNA helicase BLM (EC 5.6.2.4) (Bloom syndrome protein) (DNA 3'-5' helicase BLM) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)
Gene: BLM

Interactor 2: TERF2 (Q15554)
Telomeric repeat-binding factor 2 (TTAGGG repeat-binding factor 2) (Telomeric DNA-binding protein)
Gene: TERF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.678

Property	Details
Experiments	19329795, 12181313, 15229185
Identification Methods	affinity chromatography technology, pull down, enzyme linked immunosorbent assay, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000723 - telomere maintenance GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042803 - protein homodimerization activity GO:0061820 - telomeric D-loop disassembly
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1417 Hs			1 542
+	Hs
		867553 BLM_HUMAN (1-1417): 0: 898: 100.00		TERF1_HUMAN (96-541): 3.52e-133: 396: 23.94
+	Hs
		1050601 WRN_HUMAN (487-1294): 3.74e-143: 475: 23.02		TERF2_HUMAN (14-542): 0: 610: 100.00
+	Hs
		134056 DDX3X_HUMAN (488-1052): 1.62e-133: 428: 14.86		TERF2_HUMAN (14-542): 0: 610: 100.00
+	Hs
		294576 RECQ4_HUMAN (661-1003): 2.2e-43: 175: 34.80		TERF1_HUMAN (96-541): 3.52e-133: 396: 23.94