HitPredict

Interactor 1: BLM (P54132)
RecQ-like DNA helicase BLM (EC 5.6.2.4) (Bloom syndrome protein) (DNA 3'-5' helicase BLM) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)
Gene: BLM

Interactor 2: FANCJ (Q9BX63)
Fanconi anemia group J protein (EC 3.6.4.12) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1)
Gene: BRIP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.90 0.801

The method score is based on:

Property Details
Experiments 24895130, 21240188
Identification Methods pull down, affinity chromatography technology, anti bait coimmunoprecipitation, enzyme linked immunosorbent assay, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD_2, DEAD~Helicase_C_2
Common GO terms GO:0003677 - DNA binding
GO:0003678 - DNA helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 3 others

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Homologous interactions 0

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Last updated: 15 Jul 2024