Interactor 1: SYRC (P54136)
Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)
Gene: RARS1

Interactor 2: SYLC (Q9P2J5)
Leucine--tRNA ligase, cytoplasmic (EC 6.1.1.4) (Leucyl-tRNA synthetase) (LeuRS) (cLRS)
Gene: LARS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.705

The method score is based on:

Property Details
Experiments 28514442, 33961781, 27684187, 16055448
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006418 - tRNA aminoacylation for protein translation
GO:0017101 - aminoacyl-tRNA synthetase multienzyme complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 660
Hs

1 1176
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024