HitPredict

Interactor 1: HIRA (P54198)
Protein HIRA (TUP1-like enhancer of split protein 1)
Gene: HIRA

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	30804502, 33961781, 21724829
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1017 Hs			1 103
+	Hs
		917196 CAF1B_HUMAN (1-520): 2.28e-89: 299: 23.15		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356326 HIR1_YEAST (1-856): 9.68e-89: 304: 19.19		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Sc
		356699 CAC2_YEAST (1-423): 7.16e-88: 292: 20.29		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Hs
		917886 WDR33_HUMAN (1-201): 3.7e-33: 141: 18.32		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917881 TBL1R_HUMAN (159-398): 4.63e-34: 140: 13.84		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		918142 WDR3_HUMAN (11-167): 1.14e-24: 113: 16.56		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		245586 TBL1X_HUMAN (168-360): 7.84e-23: 106: 18.67		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		903099 WDR5_HUMAN (362-647): 5.91e-18: 88.4: 8.39		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356327 HIR2_YEAST (1-535): 8.64e-20: 97.6: 16.67		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Hs
		917722 SNR40_HUMAN (4-157): 1.3e-13: 75.7: 18.59		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Dm
		53061 A1Z898_DROME (651-852): 8.95e-10: 64.9: 9.28		H4_DROME (1-103): 4.51e-48: 150: 99.03
+	Hs
		267751 TAF5L_HUMAN (103-246): 2.83e-09: 63.2: 30.67		H4_HUMAN (1-103): 1.38e-48: 151: 100.00