HitPredict

Interactor 1: HIRA (P54198)
Protein HIRA (TUP1-like enhancer of split protein 1)
Gene: HIRA

Interactor 2: UBN2 (Q6ZU65)
Ubinuclein-2
Gene: UBN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	24981860, 33961781, 19029251
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1017 Hs			1 1347
+	Hs
		867895 HIRA_HUMAN (1-1017): 0: 779: 100.00		UBN1_HUMAN (773-1345): 3.71e-12: 73.2: 14.95
+	Hs
		1172642 SNR40_HUMAN (4-157): 1.3e-13: 75.7: 18.59		UBN2_HUMAN (1-1347): 0: 768: 100.00
+	Dm
		184534 HIRA_DROME (1-1017): 4.79e-116: 384: 32.91		YEMA_DROME (426-1021): 6.66e-55: 211: 18.14
+	Hs
		903354 WDR5_HUMAN (362-647): 5.91e-18: 88.4: 8.39		ANKH1_HUMAN (657-1320): 9.41e-29: 128: 12.24
+	Hs
		1147485 NLE1_HUMAN (724-858): 6.84e-16: 83.8: 9.03		ARID2_HUMAN (663-1291): 2.26e-28: 126: 14.03
+	Hs
		1056974 WDR33_HUMAN (1-201): 3.7e-33: 141: 18.32		MDC1_HUMAN (741-1257): 8.44e-09: 62.7: 14.66
+	Hs
		1147471 SNR40_HUMAN (4-157): 1.3e-13: 75.7: 18.59		ARID2_HUMAN (663-1291): 2.26e-28: 126: 14.03
+	Hs
		903374 WDR5_HUMAN (362-647): 5.91e-18: 88.4: 8.39		KMT2C_HUMAN (855-1346): 4.26e-15: 83.3: 12.31
+	Mm
		903669 WDR5_MOUSE (362-647): 5.91e-18: 88.4: 8.39		KMT2C_MOUSE (955-1346): 3.03e-10: 67.5: 9.18
+	Hs
		903530 WDR5_HUMAN (362-647): 5.91e-18: 88.4: 8.39		TENS1_HUMAN (710-1346): 2.29e-09: 64.3: 12.70
+	Hs
		1288325 SNR40_HUMAN (4-157): 1.3e-13: 75.7: 18.59		UBN1_HUMAN (773-1345): 3.71e-12: 73.2: 14.95
+	Hs
		1056932 SNR40_HUMAN (4-157): 1.3e-13: 75.7: 18.59		MDC1_HUMAN (741-1257): 8.44e-09: 62.7: 14.66