HitPredict

Interactor 1: VMAT1 (P54219)
Chromaffin granule amine transporter (Solute carrier family 18 member 1) (Vesicular amine transporter 1) (VAT1)
Gene: SLC18A1

Interactor 2: S12A9 (Q9BXP2)
Solute carrier family 12 member 9 (Cation-chloride cotransporter 6) (hCCC6) (Cation-chloride cotransporter-interacting protein 1) (CCC-interacting protein 1) (hCIP1) (Potassium-chloride transporter 9) (WO3.3)
Gene: SLC12A9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 525 Hs			1 914
+	Hs
		134685 NPT3_HUMAN (140-456): 2.62e-18: 89.5: 15.10		S12A6_HUMAN (1-912): 0: 734: 23.35
+	Hs
		134688 NPT3_HUMAN (140-456): 2.62e-18: 89.5: 15.10		S12A4_HUMAN (1-912): 0: 725: 22.83
+	Hs
		134695 NPT3_HUMAN (140-456): 2.62e-18: 89.5: 15.10		S12A7_HUMAN (1-912): 0: 718: 22.94
+	Hs
		985369 VMAT2_HUMAN (8-522): 1.38e-79: 259: 62.91		YLAT2_HUMAN (7-517): 1.01e-105: 339: 12.17
+	Hs
		676537 VMAT2_HUMAN (8-522): 1.38e-79: 259: 62.91		CTR1_HUMAN (13-443): 7.98e-97: 319: 16.59
+	Hs
		868014 VMAT1_HUMAN (1-525): 8.22e-86: 276: 100.00		CTR3_HUMAN (7-443): 9.26e-89: 297: 18.57
+	Hs
		1266499 S22A4_HUMAN (7-520): 1.02e-56: 200: 11.07		YLAT2_HUMAN (7-517): 1.01e-105: 339: 12.17
+	Hs
		854910 S22A4_HUMAN (7-520): 1.02e-56: 200: 11.07		CTR2_HUMAN (26-443): 1.01e-94: 314: 16.63
+	Hs
		1264245 S22A4_HUMAN (7-520): 1.02e-56: 200: 11.07		CTR3_HUMAN (7-443): 9.26e-89: 297: 18.57
+	Hs
		134668 NPT3_HUMAN (140-456): 2.62e-18: 89.5: 15.10		CTR3_HUMAN (7-443): 9.26e-89: 297: 18.57