Interactor 1: ATX3 (P54252)
Ataxin-3 (EC 3.4.19.12) (Machado-Joseph disease protein 1) (Spinocerebellar ataxia type 3 protein)
Gene: ATXN3

Interactor 2: NEDD8 (Q15843)
NEDD8 (Neddylin) (Neural precursor cell expressed developmentally down-regulated protein 8) (NEDD-8) (Ubiquitin-like protein Nedd8)
Gene: NEDD8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.680

The method score is based on:

Property Details
Experiments 17935801
Identification Methods two hybrid, pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Josephin~ubiquitin, UIM~ubiquitin
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0031625 - ubiquitin protein ligase binding
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 361
Hs

1 81
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024