HitPredict

Interactor 1: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Interactor 2: LASP1 (Q14847)
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene: LASP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.698

Property	Details
Experiments	32296183, 23275563, unassigned1304, 32814053
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 815 Hs			1 261
+	Hs
		282320 ATX1_HUMAN (1-815): 0: 1349: 100.00		NEBL_HUMAN (36-261): 8.63e-29: 116: 31.67
+	Hs
		868807 ATX1_HUMAN (1-815): 0: 1349: 100.00		BAIP2_HUMAN (19-261): 1.26e-24: 104: 15.75
+	Hs
		868562 ATX1_HUMAN (1-815): 0: 1349: 100.00		STAC2_HUMAN (12-261): 3.72e-22: 96.5: 13.10
+	Hs
		838411 ATX1_HUMAN (1-815): 0: 1349: 100.00		CRIP1_HUMAN (3-54): 2.22e-22: 89.5: 46.15
+	Hs
		857911 ATX1_HUMAN (1-815): 0: 1349: 100.00		CRIP2_HUMAN (1-54): 1.16e-17: 80.7: 42.59
+	Mm
		868968 ATX1_MOUSE (1-815): 0: 1271: 86.89		SRC8_MOUSE (59-260): 8.14e-23: 99.2: 21.68
+	Hs
		473527 ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15		STAC2_HUMAN (12-261): 3.72e-22: 96.5: 13.10
+	Dm
		1211917 Q9W3V7_DROME (574-685): 5.39e-60: 205: 44.64		LASP1_DROME (52-259): 1.57e-17: 83.8: 24.04