HitPredict

Interactor 1: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Interactor 2: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	16713569, 32814053
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 815 Hs			1 568
+	Hs
		868814 ATX1_HUMAN (1-815): 0: 1349: 100.00		KLH20_HUMAN (2-566): 1.23e-174: 509: 43.94
+	Hs
		868555 ATX1_HUMAN (1-815): 0: 1349: 100.00		KLH17_HUMAN (11-566): 1.87e-162: 479: 40.40
+	Hs
		868780 ATX1_HUMAN (1-815): 0: 1349: 100.00		KLHL8_HUMAN (5-565): 5.61e-156: 461: 37.41
+	Hs
		868607 ATX1_HUMAN (1-815): 0: 1349: 100.00		KLH36_HUMAN (379-567): 1.6e-35: 143: 25.63