HitPredict

Interactor 1: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Interactor 2: SMRC2 (Q8TAQ2)
SWI/SNF complex subunit SMARCC2 (BRG1-associated factor 170) (BAF170) (SWI/SNF complex 170 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2)
Gene: SMARCC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	16713569
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0007399 - nervous system development GO:0016363 - nuclear matrix GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 815 Hs			1 1214
+	Hs
		232063 ATX1_HUMAN (1-815): 0: 1349: 100.00		KDM1A_HUMAN (253-543): 1.97e-43: 173: 15.00
+	Hs
		868830 ATX1_HUMAN (1-815): 0: 1349: 100.00		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261449 ATX1_HUMAN (1-815): 0: 1349: 100.00		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86
+	Mm
		869040 ATX1_MOUSE (1-815): 0: 1271: 86.89		KDM1A_MOUSE (254-543): 9.03e-44: 174: 15.05
+	Hs
		473540 ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15		SMRC2_HUMAN (1-1203): 0: 992: 100.00
+	Hs
		159858 ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15		HGS_HUMAN (668-1181): 1.12e-46: 182: 19.20
+	Hs
		473582 ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15		NCOR2_HUMAN (588-1208): 2.06e-32: 139: 14.22
+	Hs
		261378 ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15		NCOR1_HUMAN (597-1154): 8.84e-32: 137: 10.86