HitPredict

Interactor 1: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Interactor 2: P121A (Q96HA1)
Nuclear envelope pore membrane protein POM 121 (Nuclear envelope pore membrane protein POM 121A) (Nucleoporin Nup121) (Pore membrane protein of 121 kDa)
Gene: POM121

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	16713569, 32814053
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 815 Hs			1 1249
+	Hs
		868739 ATX1_HUMAN (1-815): 0: 1349: 100.00		WNK1_HUMAN (36-1241): 1.45e-32: 140: 10.65
+	Hs
		868698 ATX1_HUMAN (1-815): 0: 1349: 100.00		CIC_HUMAN (128-1161): 2.11e-09: 64.5: 9.81
+	Mm
		869085 ATX1_MOUSE (1-815): 0: 1271: 86.89		SRRM2_MOUSE (364-1245): 6.61e-11: 69.5: 7.28
+	Mm
		869164 ATX1_MOUSE (1-815): 0: 1271: 86.89		CIC_MOUSE (13-1230): 1.21e-09: 65.3: 8.87
+	Mm
		868942 ATX1_MOUSE (1-815): 0: 1271: 86.89		PRC2C_MOUSE (57-1248): 7.45e-09: 62.6: 8.67
+	Hs
		473553 ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15		CIC_HUMAN (128-1161): 2.11e-09: 64.5: 9.81