HitPredict

Interactor 1: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Interactor 2: RHXF2 (Q9BQY4)
Rhox homeobox family member 2 (Paired-like homeobox protein PEPP-2) (Testis homeobox gene 1)
Gene: RHOXF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	16713569, 32814053
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid, luminescence based mammalian interactome mapping
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 815 Hs			1 288
+	Hs
		641350 ATX1_HUMAN (1-815): 0: 1349: 100.00		PAX6_HUMAN (64-288): 1.69e-31: 123: 21.15
+	Hs
		839723 ATX1_HUMAN (1-815): 0: 1349: 100.00		LHX2_HUMAN (67-272): 9.34e-32: 123: 13.11
+	Hs
		620136 ATX1_HUMAN (1-815): 0: 1349: 100.00		PAX7_HUMAN (117-286): 5.37e-30: 120: 22.94
+	Mm
		193312 ATX1_MOUSE (1-815): 0: 1271: 86.89		PHX2B_MOUSE (92-194): 9.86e-37: 134: 33.98
+	Hs
		473472 ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15		PAX6_HUMAN (64-288): 1.69e-31: 123: 21.15
+	Hs
		473469 ATX1L_HUMAN (1-815): 3.55e-108: 348: 27.15		PAX7_HUMAN (117-286): 5.37e-30: 120: 22.94
+	Dm
		1376455 Q9W3V7_DROME (574-685): 5.39e-60: 205: 44.64		Q9W2P8_DROME (141-194): 1.41e-09: 60.1: 48.15