Interactor 1: PDX1 (C6KT50)
Pyridoxal 5'-phosphate synthase subunit Pdx1 (PLP synthase subunit Pdx1) (EC 4.3.3.6)
Gene: PDX1

Interactor 2: PDX2 (Q8IIK4)
Pyridoxal 5'-phosphate synthase subunit PDX2 (PfPDX2) (EC 4.3.3.6) (Pyridoxal 5'-phosphate synthase glutaminase subunit) (EC 3.5.1.2)
Gene: PDX2

Species: Plasmodium falciparum 3D7

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16339145
Identification Methods pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SNO~SOR_SNZ
Common GO terms GO:0000304 - response to singlet oxygen
GO:0004359 - glutaminase activity
GO:0005829 - cytosol
GO:0036381 - pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity
GO:0042819 - vitamin B6 biosynthetic process
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 301
Pf

1 219
+ At
+ At
+ Sp
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Bs
+ Ph

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Last updated: 15 Jul 2024