HitPredict

Interactor 1: HAP1 (P54257)
Huntingtin-associated protein 1 (HAP-1) (Neuroan 1)
Gene: HAP1

Interactor 2: HOOK3 (Q86VS8)
Protein Hook homolog 3 (h-hook3) (hHK3)
Gene: HOOK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0015031 - protein transport
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 671 Hs			1 718
+	Hs
		725198 MYH10_HUMAN (184-651): 4.03e-10: 65.5: 12.73		HOOK3_HUMAN (1-718): 3.74e-57: 209: 100.00
+	Hs
		1231043 MRCKB_HUMAN (113-653): 1.89e-33: 139: 12.00		K2C78_HUMAN (276-606): 5.85e-21: 99.3: 19.53
+	Rn
		222476 MRCKB_RAT (113-654): 2.98e-32: 136: 11.59		MRCKA_RAT (328-718): 3.5e-21: 101: 14.08
+	Rn
		1186812 MRCKB_RAT (113-654): 2.98e-32: 136: 11.59		MRCKB_RAT (70-519): 1.55e-13: 76.5: 13.03
+	Hs
		1268126 MRCKB_HUMAN (113-653): 1.89e-33: 139: 12.00		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Hs
		230531 TRAK2_HUMAN (179-603): 3.96e-27: 119: 25.91		HOOK1_HUMAN (196-712): 4.3e-14: 78.1: 12.98
+	Hs
		725097 MYH11_HUMAN (177-610): 1.75e-18: 92.5: 11.80		MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71
+	Hs
		528435 MYH4_HUMAN (146-653): 2.39e-10: 66.3: 11.18		MYH8_HUMAN (289-718): 2.07e-17: 89.3: 10.27
+	Hs
		725095 MYH10_HUMAN (184-651): 4.03e-10: 65.5: 12.73		MYH10_HUMAN (308-718): 3.14e-15: 82.3: 10.71
+	Dm
		1303379 MYSN_DROME (151-615): 1.25e-13: 77.1: 14.11		MYSN_DROME (49-462): 1.6e-10: 67.1: 13.60
+	Hs
		502933 MYH3_HUMAN (206-654): 2.12e-09: 63.2: 10.38		MYH4_HUMAN (279-718): 3.71e-14: 78.7: 12.89
+	Hs
		502901 MYH3_HUMAN (206-654): 2.12e-09: 63.2: 10.38		MYH6_HUMAN (425-718): 1.75e-10: 66.9: 8.16
+	Hs
		522657 MYH4_HUMAN (146-653): 2.39e-10: 66.3: 11.18		MYH7_HUMAN (39-434): 1.53e-09: 63.6: 11.79
+	Hs
		528356 MYH6_HUMAN (130-642): 2.37e-09: 62.8: 10.32		MYH6_HUMAN (425-718): 1.75e-10: 66.9: 8.16
+	Hs
		724943 MYH9_HUMAN (189-610): 1.1e-09: 64: 13.68		MY18A_HUMAN (250-691): 1.59e-09: 63.8: 17.03
+	Hs
		724994 MYH9_HUMAN (189-610): 1.1e-09: 64: 13.68		CP250_HUMAN (36-648): 2.21e-09: 63.5: 11.38
+	Hs
		724687 MYH10_HUMAN (184-651): 4.03e-10: 65.5: 12.73		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27
+	Hs
		724686 MYH9_HUMAN (189-610): 1.1e-09: 64: 13.68		MYH9_HUMAN (23-360): 8.18e-09: 61.5: 11.27