HitPredict

Interactor 1: ATN1 (P54259)
Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein)
Gene: ATN1

Interactor 2: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	16169070
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1190 Hs			1 770
+	Hs
		869458 ATN1_HUMAN (1-1190): 1.67e-152: 490: 100.00		TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42
+	Hs
		869460 ATN1_HUMAN (1-1190): 1.67e-152: 490: 100.00		TLE5_HUMAN (1-200): 1.21e-91: 287: 64.50
+	Hs
		980660 RERE_HUMAN (2-779): 1.36e-10: 68.3: 10.24		TLE1_HUMAN (1-770): 0: 594: 100.00
+	Hs
		869446 ATN1_HUMAN (1-1190): 1.67e-152: 490: 100.00		WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37
+	Hs
		903345 Q86V38_HUMAN (1-1190): 4.18e-151: 486: 98.83		WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37
+	Hs
		980896 RERE_HUMAN (2-779): 1.36e-10: 68.3: 10.24		TLE3_HUMAN (1-770): 3.93e-176: 526: 77.42
+	Hs
		869506 ATN1_HUMAN (1-1190): 1.67e-152: 490: 100.00		SNR40_HUMAN (507-675): 1.08e-09: 62.8: 28.18
+	Hs
		903530 TENS1_HUMAN (14-742): 6.96e-30: 131: 17.83		WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37
+	Hs
		903374 KMT2C_HUMAN (73-701): 1.56e-19: 97.8: 17.13		WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37
+	Hs
		903576 RERE_HUMAN (2-779): 1.36e-10: 68.3: 10.24		WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37
+	Hs
		903229 NCOA6_HUMAN (260-799): 2.05e-10: 67.5: 8.99		WDR5_HUMAN (655-769): 2.57e-36: 141: 21.37
+	Mm
		903669 KMT2C_MOUSE (3-558): 3.12e-10: 67.1: 11.03		WDR5_MOUSE (655-769): 2.57e-36: 141: 21.37