HitPredict

Interactor 1: PMS1 (P54277)
PMS1 protein homolog 1 (DNA mismatch repair protein PMS1)
Gene: PMS1

Interactor 2: FAN1 (Q9Y2M0)
Fanconi-associated nuclease 1 (EC 3.1.21.-) (EC 3.1.4.1) (FANCD2/FANCI-associated nuclease 1) (hFAN1) (Myotubularin-related protein 15)
Gene: FAN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	26496610, 27880917, 25659891, 20603073, 20603015
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 932 Hs			1 1017
+	Hs
		776432 MLH1_HUMAN (1-525): 1e-135: 426: 19.27		FAN1_HUMAN (1-1017): 0: 1709: 100.00
+	Hs
		1355320 MLH3_HUMAN (1-478): 1.73e-122: 407: 21.44		FAN1_HUMAN (1-1017): 0: 1709: 100.00
+	Hs
		869902 PMS2_HUMAN (1-580): 8.15e-124: 397: 22.76		FAN1_HUMAN (1-1017): 0: 1709: 100.00
+	Mm
		1149112 MLH1_MOUSE (1-401): 1.4e-134: 423: 21.93		FAN1_MOUSE (1-1016): 0: 1629: 71.29
+	Mm
		1148439 Q68FG1_MOUSE (1-478): 1.88e-101: 347: 19.72		FAN1_MOUSE (1-1016): 0: 1629: 71.29
+	Hs
		110648 PMS2_HUMAN (1-580): 8.15e-124: 397: 22.76		H3BQ24_HUMAN (1-412): 0: 695: 99.76