HitPredict

Interactor 1: AP3D (P54362)
AP-3 complex subunit delta (Delta adaptin subunit of AP-3) (Delta-adaptin) (Garnet protein)
Gene: g

Interactor 2: ARF1 (P61209)
ADP-ribosylation factor 1 (EC 3.6.5.2)
Gene: ARF1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22291037
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Adaptin_N~Arf
Common GO terms	GO:0005795 - Golgi stack GO:0005829 - cytosol GO:0006897 - endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1034 Dm			1 182
+	Dm
		778362 AP3D_DROME (1-1034): 0: 707: 100.00		ARF4_DROME (1-180): 1.77e-69: 210: 81.67
+	Hs
		150205 AP3D1_HUMAN (1-957): 0: 565: 54.72		ARF5_HUMAN (1-180): 6.86e-79: 234: 79.44
+	Hs
		150201 AP3D1_HUMAN (1-957): 0: 565: 54.72		ARF6_HUMAN (5-179): 1.26e-75: 225: 69.71
+	Hs
		150198 AP3D1_HUMAN (1-957): 0: 565: 54.72		ARF3_HUMAN (1-181): 5.62e-69: 209: 93.37
+	Hs
		150204 AP3D1_HUMAN (1-957): 0: 565: 54.72		ARF1_HUMAN (1-181): 3.83e-69: 209: 95.58
+	Hs
		150172 AP3D1_HUMAN (1-957): 0: 565: 54.72		ARF4_HUMAN (1-180): 3.76e-66: 201: 81.67
+	Hs
		212615 AP1G1_HUMAN (18-774): 9.32e-174: 530: 18.53		ARF6_HUMAN (5-179): 1.26e-75: 225: 69.71
+	Hs
		212618 AP1G1_HUMAN (18-774): 9.32e-174: 530: 18.53		ARF1_HUMAN (1-181): 3.83e-69: 209: 95.58
+	Hs
		912839 AP2B1_HUMAN (32-750): 9.3e-161: 500: 15.35		ARF6_HUMAN (5-179): 1.26e-75: 225: 69.71
+	Dm
		778364 Q24253_DROME (32-829): 6.81e-160: 497: 14.84		ARF4_DROME (1-180): 1.77e-69: 210: 81.67
+	Dm
		897433 Q24253_DROME (32-829): 6.81e-160: 497: 14.84		ARF1_DROME (1-182): 1.55e-69: 210: 100.00
+	Hs
		912875 AP1B1_HUMAN (32-748): 3.86e-153: 481: 17.24		ARF6_HUMAN (5-179): 1.26e-75: 225: 69.71
+	Hs
		950481 AP1B1_HUMAN (32-748): 3.86e-153: 481: 17.24		ARF1_HUMAN (1-181): 3.83e-69: 209: 95.58
+	Hs
		321520 AP2A1_HUMAN (17-764): 8.37e-145: 459: 20.08		ARF6_HUMAN (5-179): 1.26e-75: 225: 69.71
+	Sc
		503154 AP3D_YEAST (11-863): 2.78e-153: 480: 27.86		ARF1_YEAST (1-179): 6.19e-67: 204: 79.33
+	Dm
		778369 Q7KVR8_DROME (2-591): 6.47e-148: 467: 20.42		ARF4_DROME (1-180): 1.77e-69: 210: 81.67
+	Dm
		897446 Q7KVR8_DROME (2-591): 6.47e-148: 467: 20.42		ARF1_DROME (1-182): 1.55e-69: 210: 100.00
+	Hs
		913190 AP4E1_HUMAN (15-654): 7.3e-134: 434: 22.19		ARF6_HUMAN (5-179): 1.26e-75: 225: 69.71
+	Hs
		897418 AP4E1_HUMAN (15-654): 7.3e-134: 434: 22.19		ARF3_HUMAN (1-181): 5.62e-69: 209: 93.37
+	Hs
		574776 AP4E1_HUMAN (15-654): 7.3e-134: 434: 22.19		ARF4_HUMAN (1-180): 3.76e-66: 201: 81.67