Interactor 1: SYYC (P54577)
Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) [Cleaved into: Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed]
Gene: YARS1

Interactor 2: SYYC (P54577)
Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) [Cleaved into: Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed]
Gene: YARS1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 25533949
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains tRNA-synt_1b~tRNA-synt_1b, tRNA_bind~tRNA_bind
Common GO terms GO:0000049 - tRNA binding
GO:0003723 - RNA binding
GO:0004831 - tyrosine-tRNA ligase activity
GO:0005153 - interleukin-8 receptor binding
GO:0005524 - ATP binding
and 10 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 528
Hs

1 528
+ Hs
+ Sc
+ Ec
+ Hs
+ Gs
+ Cj
+ Nc
+ Mp
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024