HitPredict

Interactor 1: SYYC (P54577)
Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS) [Cleaved into: Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed]
Gene: YARS1

Interactor 2: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	31478661, 31871319
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 528 Hs			1 191
+	Hs
		870690 SYYC_HUMAN (1-528): 0: 545: 100.00		RHOJ_HUMAN (2-188): 2.67e-85: 252: 64.17
+	Hs
		870635 SYYC_HUMAN (1-528): 0: 545: 100.00		RAC1_HUMAN (1-191): 1.75e-84: 249: 70.31
+	Hs
		870630 SYYC_HUMAN (1-528): 0: 545: 100.00		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48
+	Hs
		894611 SYYM_HUMAN (5-389): 9.2e-72: 238: 13.49		CDC42_HUMAN (1-191): 4.96e-82: 243: 100.00
+	Hs
		951480 SYYM_HUMAN (5-389): 9.2e-72: 238: 13.49		RHOG_HUMAN (1-191): 7.59e-82: 242: 60.73
+	Hs
		901070 SYYM_HUMAN (5-389): 9.2e-72: 238: 13.49		RHOA_HUMAN (5-191): 3.88e-81: 240: 53.48