Interactor 1: MAOX (P48163)
NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40) (Malic enzyme 1)
Gene: ME1
Interactor 2: MAOX (P48163)
NADP-dependent malic enzyme (NADP-ME) (EC 1.1.1.40) (Malic enzyme 1)
Gene: ME1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.72 | 1.00 | 0.849 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, unassigned1304, 34547241 |
| Identification Methods | two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, molecular sieving |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | malic~malic, Malic_M~malic, Malic_M~Malic_M |
| Common GO terms | GO:0000287 - magnesium ion binding GO:0004470 - malic enzyme activity GO:0004473 - malate dehydrogenase (decarboxylating) (NADP+) activity GO:0005737 - cytoplasm GO:0005739 - mitochondrion and 16 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
