HitPredict

Interactor 1: UBP14 (P54578)
Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14)
Gene: USP14

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31901637
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0045202 - synapse GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 156
+	Mm
		477036 UBP14_MOUSE (1-494): 4.66e-144: 424: 96.76		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Rn
		1137273 Q5U2N2_RAT (1-494): 8.11e-144: 423: 96.56		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Hs
		474968 UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	Hs
		924201 UBP36_HUMAN (65-482): 3.73e-90: 299: 17.54		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	At
		1091915 UBP6_ARATH (1-483): 1.59e-115: 350: 41.28		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Hs
		905374 UBP46_HUMAN (61-483): 1.58e-95: 295: 18.76		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Rn
		94336 UBP46_RAT (61-483): 9.72e-96: 295: 18.76		RL40_RAT (1-125): 5.33e-44: 142: 64.80
+	Mm
		476893 UBP47_MOUSE (28-490): 1.75e-89: 300: 17.89		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Mm
		477008 UBP12_MOUSE (61-484): 1.28e-96: 298: 18.49		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Mm
		476865 UBP8_MOUSE (42-489): 3.8e-89: 296: 17.86		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Mm
		476741 UBP46_MOUSE (61-483): 1.58e-95: 295: 18.76		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Rn
		1137288 UBP2_RAT (36-487): 3.04e-91: 292: 16.67		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	At
		1114637 UBP15_ARATH (57-483): 5.45e-84: 280: 19.55		RL40B_ARATH (1-125): 3.76e-43: 140: 62.40
+	Hs
		474982 UBP46_HUMAN (61-483): 1.58e-95: 295: 18.76		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	Mm
		476939 UBP3_MOUSE (47-491): 4.27e-89: 283: 16.63		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Hs
		271114 UBP2_HUMAN (56-487): 5.71e-90: 288: 16.30		Q5U5U6_HUMAN (1-76): 6.65e-36: 125: 100.00
+	At
		1092065 UBP15_ARATH (57-483): 5.45e-84: 280: 19.55		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Dm
		1099208 UBPE_DROME (66-489): 3.68e-87: 294: 17.53		R9PY16_DROME (1-68): 7.11e-29: 108: 91.18
+	Sc
		408408 UBP8_YEAST (105-485): 5.83e-38: 146: 20.51		RS31_YEAST (1-151): 4.55e-61: 187: 82.78