HitPredict

Interactor 1: UBP14 (P54578)
Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14)
Gene: USP14

Interactor 2: PSMD6 (Q15008)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
Gene: PSMD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	35271311, 30425250, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 389
+	Hs
		121712 UBP14_HUMAN (1-494): 7.04e-147: 431: 100.00		PSD11_HUMAN (3-387): 8.54e-77: 245: 11.03
+	Sp
		1265792 UBP6_SCHPO (3-485): 1.47e-112: 342: 36.31		RPN6_SCHPO (5-386): 3.53e-81: 256: 13.80
+	Sc
		797725 UBP6_YEAST (4-481): 1.15e-88: 282: 30.10		RPN7_YEAST (11-389): 3.41e-86: 269: 35.47
+	Sc
		797736 UBP6_YEAST (4-481): 1.15e-88: 282: 30.10		RPN6_YEAST (30-389): 1.53e-56: 192: 12.57