HitPredict

Interactor 1: UBP14 (P54578)
Ubiquitin carboxyl-terminal hydrolase 14 (EC 3.4.19.12) (Deubiquitinating enzyme 14) (Ubiquitin thioesterase 14) (Ubiquitin-specific-processing protease 14)
Gene: USP14

Interactor 2: AURKB (Q96GD4)
Aurora kinase B (EC 2.7.11.1) (Aurora 1) (Aurora- and IPL1-like midbody-associated protein 1) (AIM-1) (Aurora/IPL1-related kinase 2) (ARK-2) (Aurora-related kinase 2) (STK-1) (Serine/threonine-protein kinase 12) (Serine/threonine-protein kinase 5) (Serine/threonine-protein kinase aurora-B)
Gene: AURKB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28662510, 30425250
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 344
+	Hs
		681706 UBP8_HUMAN (42-489): 9.27e-89: 295: 18.07		AKT1_HUMAN (3-343): 6.77e-137: 399: 28.53
+	Hs
		160785 UBP42_HUMAN (59-482): 3.47e-89: 299: 17.37		AURKA_HUMAN (1-334): 2.45e-133: 387: 58.89
+	Hs
		568832 UBP22_HUMAN (66-487): 1.12e-91: 290: 19.03		KAPCA_HUMAN (36-342): 1.66e-134: 388: 26.18
+	Hs
		160291 UBP2_HUMAN (56-487): 5.71e-90: 288: 16.30		AURKA_HUMAN (1-334): 2.45e-133: 387: 58.89
+	Hs
		160631 U17L2_HUMAN (82-492): 7.98e-90: 285: 19.37		AURKA_HUMAN (1-334): 2.45e-133: 387: 58.89
+	Hs
		160840 UBP21_HUMAN (29-486): 4.53e-88: 282: 16.80		AURKA_HUMAN (1-334): 2.45e-133: 387: 58.89
+	Sc
		412790 UBP6_YEAST (4-481): 1.15e-88: 282: 30.10		KAPA_YEAST (72-328): 3.02e-51: 176: 36.12
+	Sc
		409661 UBP8_YEAST (105-485): 5.83e-38: 146: 20.51		KAPC_YEAST (72-326): 1.67e-53: 182: 39.54