HitPredict - High confidence protein-protein interactions

Interactor 1: AAKG1 (P54619)
5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1) (AMPK subunit gamma-1) (AMPKg)
Gene: PRKAG1

Interactor 2: AAKG1 (P54619)
5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1) (AMPK subunit gamma-1) (AMPKg)
Gene: PRKAG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	20562859
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	CBS~CBS
Common GO terms	GO:0004672 - protein kinase activity GO:0004691 - cAMP-dependent protein kinase activity GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 18 others more... GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006110 - regulation of glycolytic process GO:0006468 - protein phosphorylation GO:0006633 - fatty acid biosynthetic process GO:0007165 - signal transduction GO:0007283 - spermatogenesis GO:0008603 - cAMP-dependent protein kinase regulator activity GO:0010628 - positive regulation of gene expression GO:0016020 - membrane GO:0016208 - AMP binding GO:0019887 - protein kinase regulator activity GO:0019901 - protein kinase binding GO:0031588 - nucleotide-activated protein kinase complex GO:0031669 - cellular response to nutrient levels GO:0043531 - ADP binding GO:0045860 - positive regulation of protein kinase activity GO:0051170 - import into nucleus
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1	331
Hs

1	331

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Last updated: 15 Jul 2024