HitPredict

Interactor 1: AAKG1 (P54619)
5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1) (AMPK subunit gamma-1) (AMPKg)
Gene: PRKAG1

Interactor 2: AAPK2 (P54646)
5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)
Gene: PRKAA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.985

The method score is based on:

Property Details
Experiments 25416956, 17012231, 32296183, 31900314, 31983282, 32707033, 36736316, 20562859, 26186194, 28514442, 24981860, 33961781, 10698692, 31515488, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AdenylateSensor~CBS
Common GO terms GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 6 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 331
Hs

1 552
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Last updated: 15 Jul 2024