Interactor 1: AAKG1 (P54619)
5'-AMP-activated protein kinase subunit gamma-1 (AMPK gamma1) (AMPK subunit gamma-1) (AMPKg)
Gene: PRKAG1

Interactor 2: AAKB1 (Q9Y478)
5'-AMP-activated protein kinase subunit beta-1 (AMPK subunit beta-1) (AMPKb)
Gene: PRKAB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 8621713, 8663446, 26186194, 28514442, 31900314, 33961781, 10698692, 20562859, 18480843, 32296183, 21988832, 22363791, unassigned1304
Identification Methods two hybrid, pull down, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AMPK1_CBM~CBS, AMPKBI~CBS
Common GO terms GO:0004672 - protein kinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 7 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 331
Hs

1 270
+ Hs
+ Mm
+ Rn
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+ Hs
+ Hs
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+ At
+ At
+ Sp
+ Sc
+ Sc
+ Zm
+ At
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+ At

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Last updated: 15 Jul 2024