HitPredict

Interactor 1: AAPK2 (P54646)
5'-AMP-activated protein kinase catalytic subunit alpha-2 (AMPK subunit alpha-2) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31)
Gene: PRKAA2

Interactor 2: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	34079125, 33961781, 34821530
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031669 - cellular response to nutrient levels
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 552 Hs			1 161
+	Hs
		1025151 AAPK1_HUMAN (2-552): 0: 535: 74.86		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		1151925 MARK2_HUMAN (6-545): 9.52e-149: 448: 29.22		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		647911 MARK3_HUMAN (8-552): 5.72e-142: 429: 27.52		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00