HitPredict

Interactor 1: HSP72 (P54652)
Heat shock-related 70 kDa protein 2 (Heat shock 70 kDa protein 2) (Heat shock protein family A member 2)
Gene: HSPA2

Interactor 2: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33957083
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0044183 - protein folding chaperone GO:0097718 - disordered domain specific binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 639 Hs			1 412
+	Hs
		713971 HS71L_HUMAN (2-639): 0: 953: 81.90		FKBP8_HUMAN (1-412): 5.79e-102: 310: 100.00
+	Hs
		503968 HSP7C_HUMAN (3-616): 0: 946: 87.95		PPID_HUMAN (5-369): 4.48e-66: 216: 18.06
+	Hs
		871821 HSP72_HUMAN (1-639): 0: 955: 100.00		FKBPL_HUMAN (8-369): 7.94e-52: 178: 22.43
+	Hs
		504875 HSP7C_HUMAN (3-616): 0: 946: 87.95		AIPL1_HUMAN (91-370): 7.32e-49: 172: 17.33
+	Hs
		503930 HSP7C_HUMAN (3-616): 0: 946: 87.95		FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18
+	At
		1338008 HS704_ARATH (3-639): 0: 951: 73.99		HSOP1_ARATH (221-392): 1.5e-21: 98.8: 16.28
+	Hs
		684557 HSP72_HUMAN (1-639): 0: 955: 100.00		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		684439 HS71L_HUMAN (2-639): 0: 953: 81.90		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		713959 HS71L_HUMAN (2-639): 0: 953: 81.90		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		503534 HSP7C_HUMAN (3-616): 0: 946: 87.95		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		564017 HSP76_HUMAN (2-639): 0: 945: 77.45		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		871541 HSP72_HUMAN (1-639): 0: 955: 100.00		SPAG1_HUMAN (225-336): 6.7e-16: 82.1: 20.54
+	Sc
		449903 HSP73_YEAST (7-639): 0: 915: 72.22		FKBP_YEAST (99-201): 5.31e-33: 121: 32.71
+	Hs
		504028 HSP7C_HUMAN (3-616): 0: 946: 87.95		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		483776 HS71B_HUMAN (3-639): 0: 934: 83.18		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Sc
		449890 HSP73_YEAST (7-639): 0: 915: 72.22		STI1_YEAST (221-371): 6.12e-25: 108: 19.21
+	Dm
		505103 HSP7D_DROME (3-615): 0: 930: 83.36		Q9VPN5_DROME (218-345): 7.56e-18: 87.3: 19.53