HitPredict

Interactor 1: RD23A (P54725)
UV excision repair protein RAD23 homolog A (HR23A) (hHR23A)
Gene: RAD23A

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UBA~ubiquitin, ubiquitin~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 363 Hs			1 156
+	Hs
		872137 RD23A_HUMAN (1-363): 4.01e-119: 350: 100.00		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Mm
		476718 RD23A_MOUSE (1-363): 4.82e-119: 350: 94.77		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Dm
		547941 Q9V3W9_DROME (3-362): 9.91e-87: 269: 38.43		RS27A_DROME (1-156): 1.18e-72: 216: 91.03
+	Rn
		1117331 RD23B_RAT (3-363): 6.38e-109: 326: 52.05		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Mm
		476719 RD23B_MOUSE (3-363): 6.51e-108: 324: 52.52		UBC_MOUSE (1-119): 1.07e-36: 135: 67.48
+	Hs
		474969 RD23B_HUMAN (3-363): 1.37e-106: 320: 54.03		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00
+	At
		1091733 RD23C_ARATH (3-363): 1.8e-100: 305: 33.25		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	At
		1091732 RD23D_ARATH (3-363): 1.55e-99: 301: 31.23		UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81
+	Sp
		251959 RHP23_SCHPO (3-363): 2.02e-78: 247: 33.25		RS27A_SCHPO (1-151): 1.04e-57: 178: 81.46
+	Rn
		1140100 Q5XFX7_RAT (1-329): 5.04e-95: 288: 93.92		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Dm
		547946 Q9VCD5_DROME (3-362): 3.96e-58: 191: 27.90		RS27A_DROME (1-156): 1.18e-72: 216: 91.03
+	Hs
		924216 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00
+	Sp
		251961 RHP23_SCHPO (3-363): 2.02e-78: 247: 33.25		RL402_SCHPO (1-125): 7.03e-41: 135: 63.20
+	Sc
		477610 RAD23_YEAST (3-361): 1e-75: 240: 28.57		RL40A_YEAST (1-125): 2.07e-42: 139: 64.00
+	Pf
		1181547 Q8IJS8_PLAF7 (3-362): 2.53e-72: 232: 24.37		Q7KQK2_PLAF7 (1-76): 6.26e-35: 126: 98.68
+	Dm
		574854 Q9VCD5_DROME (3-362): 3.96e-58: 191: 27.90		RL40_DROME (1-125): 1.01e-43: 142: 64.80
+	Dm
		1362837 Q9VCD5_DROME (3-362): 3.96e-58: 191: 27.90		Q9W418_DROME (1-77): 1.7e-34: 127: 100.00
+	Hs
		924435 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		RL40_HUMAN (1-125): 5.33e-44: 142: 64.80
+	Rn
		88976 D4AA63_RAT (2-312): 1.73e-47: 171: 14.74		UBC_RAT (1-119): 1.57e-36: 134: 68.29
+	Hs
		475241 UBQL1_HUMAN (2-312): 9.5e-48: 171: 14.47		UBB_HUMAN (1-76): 6.65e-36: 125: 100.00