Interactor 1: RD23A (P54725)
UV excision repair protein RAD23 homolog A (HR23A) (hHR23A)
Gene: RAD23A
Interactor 2: UBP25 (Q9UHP3)
Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25)
Gene: USP25
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 1.00 | 0.948 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 25416956, 19013454, unassigned1304, 32814053, 31515488 |
| Identification Methods | two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | UCH~ubiquitin, UIM~ubiquitin |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043130 - ubiquitin binding GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process and 1 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
