Interactor 1: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Interactor 2: PSMD4 (P55036)
26S proteasome non-ATPase regulatory subunit 4 (26S proteasome regulatory subunit RPN10) (26S proteasome regulatory subunit S5A) (Antisecretory factor 1) (AF) (ASF) (Multiubiquitin chain-binding protein)
Gene: PSMD4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 14585839, 27114451, 10488153, 32296183, 12832454, 20059542, 16990800, unassigned1304
Identification Methods x-ray crystallography, affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid, cosedimentation through density gradient
Interaction Type association, physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains UIM~ubiquitin, VWA_2~ubiquitin
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0031593 - polyubiquitin modification-dependent protein binding
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 409
Hs

1 377
+ Rn
+ Hs
+ Hs
+ At
+ At
+ At
+ Zm
+ Hs
+ Dm
+ At
+ Hs
+ Xl
+ Hs
+ Hs
+ Mm
+ Dm
+ At
+ Dm
+ Ce
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024