HitPredict

Interactor 1: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Interactor 2: UBP25 (Q9UHP3)
Ubiquitin carboxyl-terminal hydrolase 25 (EC 3.4.19.12) (Deubiquitinating enzyme 25) (USP on chromosome 21) (Ubiquitin thioesterase 25) (Ubiquitin-specific-processing protease 25)
Gene: USP25

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 1.00 0.951

The method score is based on:

Property Details
Experiments 28514442, 32296183, 33961781, 28619731, 35914814, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, two hybrid fragment pooling approach, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~ubiquitin, UIM~ubiquitin
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0043130 - ubiquitin binding
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070628 - proteasome binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 409
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024