Interactor 1: CCNE (P54733)
G1/S-specific cyclin-E (DmCycE)
Gene: CycE

Interactor 2: Q7K306 (Q7K306)
Cyclin-dependent kinase 4, isoform A (EC 2.7.11.22) (Cyclin-dependent kinase 4, isoform B) (Cyclin-dependent kinase 4, isoform C) (Cyclin-dependent kinase 4, isoform D) (Cyclin-dependent kinase 4, isoform E) (LD31205p)
Gene: Cdk4

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.43 1.00 0.656

The method score is based on:

Property Details
Experiments 15575970
Identification Methods two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0046427 - positive regulation of receptor signaling pathway via JAK-STAT
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 709
Dm

1 317
+ Dm
+ Dm
+ Hs
+ Hs
+ Rn
+ Xl
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Dm
+ Mm
+ At
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024