HitPredict

Interactor 1: C9J1X0 (C9J1X0)
WD repeat-containing protein 91
Gene: WDR91

Interactor 2: HUWE1 (Q7Z6Z7)
E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)
Gene: HUWE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	26496610
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 712 Hs			1 4374
+	Hs
		59701 WDR91_HUMAN (5-712): 0: 585: 99.72		HUWE1_HUMAN (1-4374): 0: 3240: 100.00
+	Mm
		1186472 WDR91_MOUSE (5-711): 0: 544: 91.27		HUWE1_MOUSE (1-4374): 0: 3203: 96.37
+	Hs
		1192155 FBXW7_HUMAN (400-711): 2.31e-54: 200: 11.82		HUWE1_HUMAN (1-4374): 0: 3240: 100.00
+	Hs
		1192261 FZR1_HUMAN (304-511): 1.53e-16: 84.9: 14.45		HUWE1_HUMAN (1-4374): 0: 3240: 100.00
+	Hs
		125699 SKI8_HUMAN (372-598): 3.48e-72: 238: 24.12		WWP2_HUMAN (3506-4372): 0: 624: 24.57
+	Hs
		125310 WDR5_HUMAN (500-711): 3.63e-48: 174: 17.93		WWP2_HUMAN (3506-4372): 0: 624: 24.57
+	Sc
		765342 COPA_YEAST (333-600): 2.26e-37: 152: 9.97		RSP5_YEAST (3659-4372): 0: 595: 27.62
+	Hs
		1336121 FBW1A_HUMAN (271-513): 5.28e-23: 106: 12.11		SMUF1_HUMAN (3772-4371): 0: 620: 32.84
+	Hs
		1334881 FBW1A_HUMAN (271-513): 5.28e-23: 106: 12.11		SMUF2_HUMAN (3771-4371): 0: 611: 33.44
+	Hs
		267800 TAF5L_HUMAN (464-710): 3.51e-44: 169: 15.29		HECW2_HUMAN (3131-4373): 4.71e-161: 547: 20.49
+	Sc
		863628 COPA_YEAST (333-600): 2.26e-37: 152: 9.97		TOM1_YEAST (3831-4374): 1.99e-157: 554: 43.77
+	Hs
		1336118 FZR1_HUMAN (304-511): 1.53e-16: 84.9: 14.45		SMUF1_HUMAN (3772-4371): 0: 620: 32.84
+	Hs
		808327 FBW1A_HUMAN (271-513): 5.28e-23: 106: 12.11		NEDD4_HUMAN (3104-4372): 2.46e-179: 594: 21.46
+	Mm
		1321820 FZR1_MOUSE (304-503): 3.93e-16: 83.8: 14.52		SMUF1_MOUSE (3803-4371): 0: 608: 33.86
+	Sc
		561903 TUP1_YEAST (376-602): 2e-14: 79: 17.57		TOM1_YEAST (3831-4374): 1.99e-157: 554: 43.77
+	Hs
		1350502 FZR1_HUMAN (304-511): 1.53e-16: 84.9: 14.45		HECW2_HUMAN (3131-4373): 4.71e-161: 547: 20.49