Interactor 1: EPHB4 (P54760)
Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)
Gene: EPHB4

Interactor 2: EPHB1 (P54762)
Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2)
Gene: EPHB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.646

The method score is based on:

Property Details
Experiments 35384245
Identification Methods affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EphA2_TM~PK_Tyr_Ser-Thr, Ephrin_lbd~Ephrin_lbd, Ephrin_lbd~fn3, fn3~fn3, PK_Tyr_Ser-Thr~fn3, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SAM_1, SAM_1~SAM_1
Common GO terms GO:0001525 - angiogenesis
GO:0005005 - transmembrane-ephrin receptor activity
GO:0005524 - ATP binding
GO:0005576 - extracellular region
GO:0005829 - cytosol
and 6 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

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Last updated: 15 Jul 2024